Kwandwe Private Game Reserve, in South Africa's Eastern Cape, is home to the famous Big Five – lions, elephants, buffalo, leopards, and rhinoceros – as well as cheetahs, giraffes, and various antelope species. Bird enthusiasts will find over 200 bird species, including raptors and various endemic species.

Kwandwe's landscape is a mix of open plains, dense bushveld, and rolling hills, offering scenic game drives. Guided walks and nocturnal safaris provide different perspectives of the reserve’s fauna and flora. The Great Fish River, which cuts through the reserve, adds to its ecological diversity and offers additional activities like fishing.